While working on ER, he began attracting a variety of leading roles in films, including the superhero film Batman & Robin (1997) and the crime comedy Out of Sight (1998), in which he first worked with director Steven Soderbergh, who would become a long-time collaborator.
In 1999, he took the lead role in Three Kings, a well-received war satire set during the Gulf War.
And I think that's an important part of being famous.
The practical jokes have to be aimed at you." Clooney's first role was as an extra in the television mini-series Centennial in 1978, which was based on the novel of the same name by James A.
It is Clooney's most successful film with him in the lead role, earning 1 million worldwide (he appeared, but did not star, in Gravity, which has a 3 million worldwide box office).
In 2001, Clooney and Soderbergh co-founded Section Eight Productions, for which Grant Heslov was president of television.
In August 2006, Clooney and Heslov started the production company Smokehouse Pictures.The same year he directed, produced, and starred in Good Night, and Good Luck, a film about 1950s television journalist Edward R.Murrow's famous war of words with Senator Joseph Mc Carthy.He played a handyman on the series The Facts of Life and appeared as Bobby Hopkins, a detective, on an episode of The Golden Girls.His first prominent role was a semi-regular supporting role in the sitcom Roseanne, playing Roseanne Barr's supervisor Booker Brooks, followed by the role of a construction worker on Baby Talk, a co-starring role on the CBS drama Bodies of Evidence as Detective Ryan Walker, and then a year-long turn as Det. In 1988, Clooney played a role in the comedy-horror film Return of the Killer Tomatoes. Doug Ross, alongside Anthony Edwards, Julianna Margulies, and Noah Wyle, on the hit NBC medical drama ER from 1994 to 1999.Clooney won an Academy Award for Best Supporting Actor for the Middle East thriller Syriana (2005), and subsequently earned Best Actor nominations for the legal thriller Michael Clayton (2007) and the comedy-dramas Up in the Air (2009) and The Descendants (2011).In 2013, he received the Academy Award for Best Picture for producing the political thriller Argo.Clooney made his directorial debut in the 2002 film Confessions of a Dangerous Mind, based on the autobiography of TV producer Chuck Barris.Though the film did not do well at the box office, critics stated that Clooney's directing showed promise.Clooney was then cast as Batman in Joel Schumacher's Batman & Robin, which was a modest box office performer, but a critical failure (with Clooney himself calling the film "a waste of money").After leaving ER, Clooney starred in the commercially successful films The Perfect Storm (2000), a disaster drama; and O Brother, Where Art Thou? In 2001, he teamed up with Soderbergh again for the heist comedy Ocean's Eleven, a remake of the 1960s Rat Pack film of the same name, with Clooney playing Danny Ocean, originally portrayed by Frank Sinatra.